Stenting “Vulnerable” But Fractional Flow Reserve–Negative Lesions

Fractional flow reserve guided stenting of a myocardial bridge

Clinical Outcomes of Deferred Lesions With Angiographically Insignificant Stenosis But Low Fractional Flow Reserve

BACKGROUND Data are limited regarding outcomes of deferred lesions in patients with angiographically insignificant stenosis but low fractional flow reserve (FFR). We investigated the natural history of angiographically insignificant stenosis with low FFR among patients who underwent routine 3-vessel FFR measurement. METHODS AND RESULTS From December 2011 to March 2014, 1136 patients with 3298...

Baseline fractional flow reserve and stent diameter predict event rates after stenting: a further step, but still much to learn.

Stenting of bifurcation lesions

We agree that an RCT cannot be compared with a retrospective analysis. However, we do not agree on the note of natural selection bias. On the contrary, we believe that our analysis is completely unbiased because literally all patients admitted for bifurcation stenting in the year 2013 were included. In a randomised controlled trial with strict inclusion and exclusion criteria, the population is...

Clinical applications of fractional flow reserve in bifurcation lesions

Percutaneous coronary intervention (PCI) for coronary bifurcation lesions has been associated with lower procedural success rates and worse clinical outcomes compared with PCI for simple coronary lesions. Angiographic evaluation alone is sometimes inaccurate and does not reflect the functional significance of bifurcation lesions. The fractional flow reserve (FFR) is an easily obtainable, reliab...